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Peptide record

TPDB22054

ACE inhibitor from wakame ACE inhibitors Antibacterial Antidiabetic Antifungal Antihypertensive standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB22054
ACE inhibitor from wakame
ACE inhibitors Antibacterial Antidiabetic Antifungal Antihypertensive
Anti-infective peptides Cardiometabolic peptides
Peptipedia CAFPdb dbAMP AHTPDB AHTpin
standard
No
A 2-aa standard natural multi-activity (ACE inhibitors, Antibacterial, Antidiabetic, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
KL
Physicochemical Analysis
C12H25N3O3
ARNDCEQGHIMFPSTWYV
LK
259.35
10.10
1
0
1
+1
0.43
-0.050
195.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C12H25N3O3
259.35
10.10
+1
0.43
-0.050
259.3442
259.1890
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
50.20 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

2
Evidence 2 Activity

Activity

IC50
Antihypertensive
50.20 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
2
Additional Detail Fields 1 fields
2