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Peptide record

TPDB22053

Antibacterial Antiparasitic Cell-penetrating Peptides Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB22053
Antibacterial Antiparasitic Cell-penetrating Peptides Toxicity
Anti-infective peptides Toxicity and safety peptides Delivery and barrier-penetrating peptides
Peptipedia dbAMP 3.0 CPPsite3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antiparasitic, Cell-penetrating Peptides, and other sources) peptide sequence curated from Peptipedia, dbAMP 3.0, and CPPsite3.0, with an available 3D structural model.
Sequence
KKYKAYFKFKCKK
Physicochemical Analysis
C84H132N20O16S1
RNDEQGHILMPSTWV
K
1710.16
10.54
7
0
5
+7
2.38
-1.538
7.69
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
2980
174.25
3
Residue Composition
number
1
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
7
K
0
M
2
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 7 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
13
C84H132N20O16S1
1710.16
10.54
+7
2.38
-1.538
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
232.88 µM
Cytotoxic
50% Cytotoxicity | 232.88 | µM | target cell: Bone marrow-derived macrophages (BMDMs)

Target

Bone marrow-derived macrophages (BMDMs)

Source & Reference

NA
DBAASP
Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents. | Comp Biochem Physiol C Toxicol Pharmacol | 2019