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Peptide record

TPDB22020

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
50 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB22020
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 50-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KLCERPSGTWSGVCGNSNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
Physicochemical Analysis
C236H363N71O68S8
DM
C
5539.39
8.31
8
2
14
+4
6.25
-0.336
48.80
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
8980
162.11
21
Residue Composition
number
3
A
2
R
5
N
0
D
8
C
2
E
1
Q
4
G
2
H
2
I
2
L
4
K
0
M
2
F
3
P
4
S
1
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 3 R: 2 N: 5 D: 0 C: 8 E: 2 Q: 1 G: 4 H: 2 I: 2 L: 2 K: 4 M: 0 F: 2 P: 3 S: 4 T: 1 W: 1 Y: 2 V: 2
Chemical Descriptors
50
C236H363N71O68S8
5539.39
8.31
+4
6.25
-0.336
Evidence Records 24 records
Evidence 1 Activity

Activity

IC50
Antibacterial
10 µg/mL

Target

A. brassicola

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
low salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici
Evidence 2 Activity

Activity

IC50
Antibacterial
3.9 µg/mL

Target

B. cinerea

Source & Reference

dbAMP

Other

low salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC
Evidence 3 Activity

Activity

IC50
Antibacterial
3 µg/mL

Target

F. culmorum

Source & Reference

dbAMP

Other

salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahli
Evidence 4 Activity

Activity

IC50
Antibacterial
3 µg/mL

Target

p. lycopersici

Source & Reference

dbAMP

Other

(IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2
Evidence 5 Activity

Activity

IC50
Antibacterial
0.25 µg/mL

Target

P. oryzae

Source & Reference

dbAMP

Other

50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2/2023.
Evidence 6 Activity

Activity

IC50
Antibacterial
1.5 µg/mL

Target

V. dahliae

Source & Reference

dbAMP

Other

3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2/2023.
Evidence 7 Activity

Activity

IC50
Antifungal
10 µg/mL

Target

A. brassicola

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
low salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici
Evidence 8 Activity

Activity

IC50
Antifungal
3.9 µg/mL

Target

B. cinerea

Source & Reference

dbAMP CAFPdb Antifungipept

Other

low salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC
Evidence 9 Activity

Activity

IC50
Antifungal
3 µg/mL

Target

F. culmorum

Source & Reference

dbAMP CAFPdb Antifungipept

Other

salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahli
Evidence 10 Activity

Activity

IC50
Antifungal
3 µg/mL

Target

p. lycopersici

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2
Evidence 11 Activity

Activity

IC50
Antifungal
0.25 µg/mL

Target

P. oryzae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2/2023.
Evidence 12 Activity

Activity

IC50
Antifungal
1.5 µg/mL

Target

V. dahliae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2/2023.
Evidence 13 Activity

Activity

IC50
Antiparasitic
10 µg/mL

Target

A. brassicola

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici
Evidence 14 Activity

Activity

IC50
Antiparasitic
3.9 µg/mL

Target

B. cinerea

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC
Evidence 15 Activity

Activity

IC50
Antiparasitic
3 µg/mL

Target

F. culmorum

Source & Reference

NA

Other

salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahli
Evidence 16 Activity

Activity

IC50
Antiparasitic
3 µg/mL

Target

p. lycopersici

Source & Reference

NA

Other

(IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2
Evidence 17 Activity

Activity

IC50
Antiparasitic
0.25 µg/mL

Target

P. oryzae

Source & Reference

NA

Other

50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2/2023.
Evidence 18 Activity

Activity

IC50
Antiparasitic
1.5 µg/mL

Target

V. dahliae

Source & Reference

NA

Other

3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2/2023.
Evidence 19 Activity

Activity

IC50
Antiviral
10 µg/mL

Target

A. brassicola

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici
Evidence 20 Activity

Activity

IC50
Antiviral
3.9 µg/mL

Target

B. cinerea

Source & Reference

NA

Other

low salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC
Evidence 21 Activity

Activity

IC50
Antiviral
3 µg/mL

Target

F. culmorum

Source & Reference

NA

Other

salt medium A: active against A. brassicola (IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahli
Evidence 22 Activity

Activity

IC50
Antiviral
3 µg/mL

Target

p. lycopersici

Source & Reference

NA

Other

(IC50 10 ug/ml), B. cinerea (IC50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2
Evidence 23 Activity

Activity

IC50
Antiviral
0.25 µg/mL

Target

P. oryzae

Source & Reference

NA

Other

50 3.9 ug/ml), F. culmorum (IC50 3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2/2023.
Evidence 24 Activity

Activity

IC50
Antiviral
1.5 µg/mL

Target

V. dahliae

Source & Reference

NA

Other

3 ug/ml), F. oxysporum f.sp. lycopersici (IC50 3 ug/ml), P. oryzae (IC50 0.25 ug/ml), and V. dahliae (IC50 1.5 ug/ml). Activity and Seq updated 2/2023.