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Peptide record

TPDB21989

Antibacterial Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB21989
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 6-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KKWQWK
Physicochemical Analysis
C45H66N12O8
ARNDCEGHILMFPSTYV
K
903.09
10.84
3
0
2
+3
-0.15
-2.833
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
1218.03
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
6
C45H66N12O8
903.09
10.84
+3
-0.15
-2.833
Evidence Records 3 records
Evidence 1 Activity

Activity

0.5% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
0.5% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of Substituting Arginine by Lysine in Bovine Lactoferricin Derived Peptides: Pursuing Production Lower Costs, Lower Hemolysis, and Sustained Antimicrobial Activity | Int J Pept Res Ther | 2021
Evidence 2 Activity

Activity

1% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
1% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of Substituting Arginine by Lysine in Bovine Lactoferricin Derived Peptides: Pursuing Production Lower Costs, Lower Hemolysis, and Sustained Antimicrobial Activity | Int J Pept Res Ther | 2021
Evidence 3 Activity

Activity

1.5% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
1.5% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of Substituting Arginine by Lysine in Bovine Lactoferricin Derived Peptides: Pursuing Production Lower Costs, Lower Hemolysis, and Sustained Antimicrobial Activity | Int J Pept Res Ther | 2021