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Peptide record

TPDB21986

Antibacterial Antifungal Antiviral Toxicity standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB21986
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP 3.0
standard
No
A 4-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP 3.0, with an available 3D structural model.
Sequence
KKWK
Physicochemical Analysis
C29H48N8O5
ARNDCEQGHILMFPSTYV
K
588.75
10.84
3
0
1
+3
1.12
-3.150
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
934.18
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
4
C29H48N8O5
588.75
10.84
+3
1.12
-3.150
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
43.37±0.53 µg/mL
Cytotoxic
50% Cytotoxicity | 43.37±0.53 | µg/mL | target cell: Madin-Darby canine kidney cells

Target

Madin-Darby canine kidney cells

Source & Reference

NA
DBAASP
Potent Influenza A Virus Entry Inhibitors Targeting a Conserved Region of Hemagglutinin | Biochem Pharmacol | 2017