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Peptide record

TPDB21972

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB21972
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
KKVTMTCSIS
Physicochemical Analysis
C45H84N12O15S2
ARNDEQGHLFPWY
KST
1097.35
9.90
2
0
3
+2
1.81
0.230
68.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
5
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
1
I
0
L
2
K
1
M
0
F
0
P
2
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 2 M: 1 F: 0 P: 0 S: 2 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C45H84N12O15S2
1097.35
9.90
+2
1.81
0.230
Evidence Records 2 records
Evidence 1 Activity

Activity

<2% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
<2% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
In Silico Predicted Antifungal Peptides: In Vitro and In Vivo Anti- Candida Activity. | J Fungi (Basel) | 2021
Evidence 2 Activity

Activity

0% Killing
Toxicity
200 µM
Cytotoxic
0% Killing | 200 | µM | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
In Silico Predicted Antifungal Peptides: In Vitro and In Vivo Anti- Candida Activity. | J Fungi (Basel) | 2021