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Peptide record

TPDB21957

Antibacterial Antifungal Antiviral Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB21957
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
KKLVAASQAALGL
Physicochemical Analysis
C57H104N16O16
RNDCEHIMFPTWY
A
1269.55
10.60
2
0
8
+2
0.41
0.792
143.08
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
3
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 3 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C57H104N16O16
1269.55
10.60
+2
0.41
0.792
Evidence Records 4 records
Evidence 1 Activity

Activity

30% Cell death
Toxicity
100 µg/mL
Cytotoxic
30% Cell death | 100 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Antiviral Activity of Synthetic Peptides Derived from Physiological Proteins. | Intervirology | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
A Peptide Found in Human Serum, Derived from the C-Terminus of Albumin, Shows Antifungal Activity In Vitro and In Vivo. | Microorganisms | 2020
Evidence 3 Activity

Activity

1.09% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
1.09% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Peptide Found in Human Serum, Derived from the C-Terminus of Albumin, Shows Antifungal Activity In Vitro and In Vivo. | Microorganisms | 2020
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.30654366]30% cytotoxicity against Vero cells at the concentration of 100µg/ mL.

Source & Reference

NA
DRAMP
Intervirology. 2018 61(4):166-173.