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Peptide record

TPDB21944

Antibacterial Antifungal Toxicity modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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TPDB21944
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 10-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
KKLKXHKKLQ
Physicochemical Analysis
C53H99N17O11
ARNDCEGIMFPSTWYV
K
1150.48
11.12
6
0
2
+5
5.37
-1.860
78.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
0
I
2
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 2 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C53H99N17O11
1150.48
11.12
+5
5.37
-1.860
Evidence Records 8 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
3% Hemolysis | 150 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 2 Activity

Activity

4% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
4% Hemolysis | 250 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 3 Activity

Activity

5% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
5% Hemolysis | 150 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 4 Activity

Activity

16% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
16% Hemolysis | 250 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 5 Activity

Activity

6% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
6% Hemolysis | 150 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 6 Activity

Activity

8% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
8% Hemolysis | 250 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 7 Activity

Activity

34% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
34% Hemolysis | 150 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 8 Activity

Activity

40% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
40% Hemolysis | 250 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016