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Peptide record

TPDB21941

Antibacterial Antifungal Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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TPDB21941
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
KKLKKLXHKKLQ
Physicochemical Analysis
C65H122N20O13
ARNDCEGIMFPSTWYV
K
1391.81
11.21
7
0
3
+6
5.80
-1.558
97.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
0
I
3
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 3 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C65H122N20O13
1391.81
11.21
+6
5.80
-1.558
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
0% Hemolysis | 150 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 2 Activity

Activity

7% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
7% Hemolysis | 250 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 3 Activity

Activity

3% Hemolysis
Toxicity
150-250 µM
Hemolytic Cytotoxic
3% Hemolysis | 150-250 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016