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Peptide record

TPDB21940

Antibacterial Antifungal Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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TPDB21940
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
KKLKKLXFKKLQ
Physicochemical Analysis
C68H124N18O13
ARNDCEGHIMPSTWYV
K
1401.85
11.21
6
0
4
+6
3.71
-1.058
97.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
3
L
6
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 3 K: 6 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C68H124N18O13
1401.85
11.21
+6
3.71
-1.058
Evidence Records 2 records
Evidence 1 Activity

Activity

93% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
93% Hemolysis | 150 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016
Evidence 2 Activity

Activity

100% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
100% Hemolysis | 250 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Synthetic Cyclolipopeptides Selective against Microbial, Plant and Animal Cell Targets by Incorporation of D-Amino Acids or Histidine. | PLoS One | 2016