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Peptide record

TPDB21927

Antibacterial Hemolysis Toxicity standard
52 amino acids
Basic Information
3D PDB MODEL
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TPDB21927
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 52-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, HemoPI, Hemolytic2, and other sources, with an available 3D structural model.
Sequence
KKLFKKILKYLAGPAKKLFKKILKYLAGPAKDWEHLKDWEHLKDWEHLKDEL
Physicochemical Analysis
C305H477N75O71
RNCQMSTV
K
6330.60
10.13
17
8
23
+6
14.07
-0.802
97.69
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
19480
307.71
2
Residue Composition
number
4
A
0
R
0
N
4
D
0
C
4
E
0
Q
2
G
3
H
2
I
10
L
14
K
0
M
2
F
2
P
0
S
0
T
3
W
2
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 4 C: 0 E: 4 Q: 0 G: 2 H: 3 I: 2 L: 10 K: 14 M: 0 F: 2 P: 2 S: 0 T: 0 W: 3 Y: 2 V: 0
Chemical Descriptors
52
C305H477N75O71
6330.60
10.13
+6
14.07
-0.802
Evidence Records 4 records
Evidence 1 Activity

Activity

49% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
49% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 2 Activity

Activity

84% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
84% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 3 Activity

Activity

92% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
92% Hemolysis | 250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Derivatives of the antimicrobial peptide BP100 for expression in plant systems. | PLoS One | 2013
Evidence 4 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis