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Peptide record

TPDB21914

Antibacterial Toxicity modified_plain modified
7 amino acids
Basic Information
3D PDB MODEL
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TPDB21914
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 7-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KKKXXYX
Physicochemical Analysis
C27H47N7O6
ARNDCEQGHILMFPSTWV
K
565.71
10.46
3
0
1
+3
2.03
-1.857
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
263.38
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
7
C27H47N7O6
565.71
10.46
+3
2.03
-1.857
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
10% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections. | Sci Rep | 2019
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
56 µM
Hemolytic Cytotoxic
50% Hemolysis | 56 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections. | Sci Rep | 2019
Evidence 3 Activity

Activity

54% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
54% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization, mechanism of action and optimization of activity of a novel peptide-peptoid hybrid against bacterial pathogens involved in canine skin infections. | Sci Rep | 2019