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Peptide record

TPDB21893

Antibacterial Anticancer Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB21893
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KKKKRRXXKKWRKWLAKK
Physicochemical Analysis
C103H182N36O17
NDCEQGHIMFPSTYV
K
2196.81
12.74
12
0
4
+12
6.91
-2.489
27.22
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
500.73
0
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
9
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 9 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
18
C103H182N36O17
2196.81
12.74
+12
6.91
-2.489
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
60 µM
Cytotoxic
50% Cell death | 60 | µM | target cell: Human diploid fibroblasts HFW

Target

Human diploid fibroblasts HFW

Source & Reference

NA
DBAASP
Novel antimicrobial peptides with high anticancer activity and selectivity. | PLoS One | 2015
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel antimicrobial peptides with high anticancer activity and selectivity. | PLoS One | 2015