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Peptide record

TPDB21886

Antibacterial Antifungal Toxicity standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB21886
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 10-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KKKKKRAHQQ
Physicochemical Analysis
C55H102N22O13
NDCEGILMFPSTWYV
K
1279.55
11.85
7
0
1
+6
7.71
-3.240
10.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
2
Q
0
G
1
H
0
I
0
L
5
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 1 I: 0 L: 0 K: 5 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C55H102N22O13
1279.55
11.85
+6
7.71
-3.240
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
256.05 ± 3.57 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 256.05 ± 3.57 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design, synthesis, antifungal evaluation and docking studies of antifungal peptide CGA-N12 analogues based on the target CtKRE9. | Bioorg Chem | 2023