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Peptide record

TPDB21879

K6 Antibacterial Cell-penetrating Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB21879
K6
Antibacterial Cell-penetrating Peptides
Anti-infective peptides Delivery and barrier-penetrating peptides
Peptipedia CPPsite3.0
standard
No
A 7-aa standard natural multi-activity (Antibacterial and Cell-penetrating Peptides) peptide sequence curated from Peptipedia and CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
KKKKKKK-NH2
Physicochemical Analysis
C42H86N14O8
ARNDCEQGHILMFPSTWYV
K
915.23
11.29
7
0
0
+7
6.93
-3.900
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
7
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
7
C42H86N14O8
915.23
11.29
+7
6.93
-3.900
Amidation
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Escherichia Coli K-12 cell

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
FAM group at the ε-amino K* of C terminus
Cytoplasm
Lower green fluorescence corresponding to FAM of 0.7 ± 0.34%
In vitro
CCCSSSTTCCCTTTTC
Additional Detail Fields 1 fields
CCCSSSTTCCCTTTTC