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Peptide record

TPDB21878

Antibacterial Toxicity modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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TPDB21878
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 17-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KKKKKKAGFXAWGXFGA
Physicochemical Analysis
C80H126N22O16
RNDCEQHILMPSTYV
K
1652.02
11.21
6
0
6
+6
1.35
-0.853
17.65
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
332.93
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
0
L
6
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 6 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C80H126N22O16
1652.02
11.21
+6
1.35
-0.853
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
<5% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides. | Bioorg Med Chem | 2018