Back to search

Peptide record

TPDB21876

Antibacterial Toxicity modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21876
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 17-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KKKKKKAAFXAWAXFAA
Physicochemical Analysis
C83H132N22O16
RNDCEQGHILMPSTYV
AK
1694.10
11.21
6
0
9
+6
0.81
-0.465
35.29
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
324.66
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
6
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 6 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17
C83H132N22O16
1694.10
11.21
+6
0.81
-0.465
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
3.8 µM
Hemolytic Cytotoxic
<5% Hemolysis | 3.8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Influence of hydrocarbon-stapling on membrane interactions of synthetic antimicrobial peptides. | Bioorg Med Chem | 2018