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Peptide record

TPDB21867

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB21867
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KKIWKKWIKKIIKI
Physicochemical Analysis
C94H161N23O15
ARNDCEQGHLMFPSTYV
K
1853.46
11.29
7
0
7
+7
1.68
-0.471
139.29
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
11000
593.49
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
5
I
0
L
7
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 5 L: 0 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
14
C94H161N23O15
1853.46
11.29
+7
1.68
-0.471
Evidence Records 2 records
Evidence 1 Activity

Activity

8% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
8% Hemolysis | 200 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria | Antibiotics (Basel) | 2022
Evidence 2 Activity

Activity

10% Cytotoxicity
Toxicity
100 µM
Cytotoxic
10% Cytotoxicity | 100 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Design of Antimicrobial Peptides with Cell-Selective Activity and Membrane-Acting Mechanism against Drug-Resistant Bacteria | Antibiotics (Basel) | 2022