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Peptide record

TPDB21863

Antibacterial standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB21863
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 9-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KKIRVRLSA
Physicochemical Analysis
C47H91N17O11
NDCEQGHMFPTWY
RK
1070.35
12.42
4
0
4
+4
2.76
-0.367
130.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
2
K
0
M
0
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 2 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
9
C47H91N17O11
1070.35
12.42
+4
2.76
-0.367
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.7-1.5 µM

Target

Escherichia coli ATCC 25922 or W03BG0025

Source & Reference

NA

Other

active against E. coli ATCC 25922 or W03BG0025 (MIC 0.7-1.5 uM), P. aeruginosa ATCC 27853 or PAO1 or 10 more strains (MIC 0.3-1.5 uM, MIC90 1.4 uM from 7
Evidence 2 Activity

Activity

MIC
Antibacterial
1.5-3.0 µM

Target

A. baumannii RUH 134 or 875 or MR157

Source & Reference

NA

Other

e 7086042 or ATCC 13833 or 2 more strains (MIC 1.5-3.0 uM MIC90 2.8 uM from 73 strains), A. baumannii RUH 134 or 875 or MR157 (MIC 1.5-3.0 uM), P-mirabilis W03VA1017S (MIC > 24 uM), E. aerogenes W03BG0067 (MIC 1.5 uM), E. cloacae W0
Evidence 3 Activity

Activity

MIC
Antibacterial
1.5 µM

Target

Enterobacter aerogenes W03BG0067

Source & Reference

NA

Other

baumannii RUH 134 or 875 or MR157 (MIC 1.5-3.0 uM), P-mirabilis W03VA1017S (MIC > 24 uM), E. aerogenes W03BG0067 (MIC 1.5 uM), E. cloacae W03AN0041 (MIC 1.5 uM), B-cepacia ORB-99 (MIC > 24 uM), S-marcescens W03BG000
Evidence 4 Activity

Activity

MIC
Antibacterial
1.5 µM

Target

Enterobacter cloacae W03AN0041

Source & Reference

NA

Other

C 1.5-3.0 uM), P-mirabilis W03VA1017S (MIC > 24 uM), E. aerogenes W03BG0067 (MIC 1.5 uM), E. cloacae W03AN0041 (MIC 1.5 uM), B-cepacia ORB-99 (MIC > 24 uM), S-marcescens W03BG0003 (MIC> 24 uM), S. aureus ATCC 2921
Evidence 5 Activity

Activity

MIC
Antibacterial
6 µM

Target

Staphylococcus aureus ATCC 29213 or 3851

Source & Reference

NA

Other

AN0041 (MIC 1.5 uM), B-cepacia ORB-99 (MIC > 24 uM), S-marcescens W03BG0003 (MIC> 24 uM), S. aureus ATCC 29213 or 3851 (MIC 6 uM).