Back to search

Peptide record

TPDB21851

Antibacterial Toxicity modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21851
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 11-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KKFXWWWXFKK
Physicochemical Analysis
C75H98N16O10
ARNDCEQGHILMPSTYV
K
1383.70
11.00
4
0
5
+4
-3.85
-1.155
0.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
1192.45
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
4
K
0
M
2
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 4 M: 0 F: 2 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
11
C75H98N16O10
1383.70
11.00
+4
-3.85
-1.155
Evidence Records 1 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
>200 µM
Hemolytic Cytotoxic
<5% Hemolysis | >200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidin-derived Trp/Pro-rich antimicrobial peptides with lysine peptoid residue (Nlys): therapeutic index and plausible mode of action | J Pept Sci | 2007