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Peptide record

TPDB21825

Antibacterial Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB21825
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
KIGAKIKIGAKXKIGAKI
Physicochemical Analysis
C81H153N23O18
RNDCEQHLMFPSTWYV
K
1737.25
11.21
6
0
8
+6
3.91
0.183
125.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
5
I
0
L
6
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 5 L: 0 K: 6 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C81H153N23O18
1737.25
11.21
+6
3.91
0.183
Evidence Records 4 records
Evidence 1 Activity

Activity

17% Hemolysis
Toxicity
7.5 µM
Hemolytic Cytotoxic
17% Hemolysis | 7.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes. | Phys Chem Chem Phys | 2013
Evidence 2 Activity

Activity

38% Hemolysis
Toxicity
60 µM
Hemolytic Cytotoxic
38% Hemolysis | 60 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes. | Phys Chem Chem Phys | 2013
Evidence 3 Activity

Activity

5% Hemolysis
Toxicity
7.5 µM
Hemolytic Cytotoxic
5% Hemolysis | 7.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes. | Phys Chem Chem Phys | 2013
Evidence 4 Activity

Activity

7% Hemolysis
Toxicity
60 µM
Hemolytic Cytotoxic
7% Hemolysis | 60 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Stereochemical effects on the aggregation and biological properties of the fibril-forming peptide [KIGAKI]3 in membranes. | Phys Chem Chem Phys | 2013