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Peptide record

TPDB21793

Antibacterial Antifungal standard
117 amino acids
Basic Information
3D PDB MODEL
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TPDB21793
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 117-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
KGSSSSSSSSRSSSSSYRSSGSSYRSPGSSYRSSGSYGTSGSRLSGIRPSSRSYRTGFRTAGSVGPATRPFTRPTGPLKPISRPPSRAACYSCYSASSATAIQCCTHYSLCCNLVKG
Physicochemical Analysis
C504H805N163O173S6
DEMW
S
12108.28
10.81
17
0
26
+16
10.12
-0.640
34.27
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
12295
101.54
61
Residue Composition
number
7
A
13
R
1
N
0
D
6
C
0
E
1
Q
12
G
1
H
3
I
4
L
3
K
0
M
2
F
9
P
37
S
8
T
0
W
8
Y
2
V
Amino Acid Distribution
A: 7 R: 13 N: 1 D: 0 C: 6 E: 0 Q: 1 G: 12 H: 1 I: 3 L: 4 K: 3 M: 0 F: 2 P: 9 S: 37 T: 8 W: 0 Y: 8 V: 2
Chemical Descriptors
117
C504H805N163O173S6
12108.28
10.81
+16
10.12
-0.640
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

MjPen-II binds to bacterial surface polysaccharides to promote bacterial agglutination (bacteria-agglutinating). The Ser-rich region enhances the agglutination activity of MjPen-II, but had no agglutination activity by itself. Antibacterial: Active against Gram- E. coli, K. pneumoniae, P. aeruginosa, V. anguillarum, Gram+ B. megaterium, B. subtilis, S. aureus. Updated 12/2016.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

MjPen-II binds to bacterial surface polysaccharides to promote bacterial agglutination (bacteria-agglutinating). The Ser-rich region enhances the agglutination activity of MjPen-II, but had no agglutination activity by itself. Antibacterial: Active against Gram- E. coli, K. pneumoniae, P. aeruginosa, V. anguillarum, Gram+ B. megaterium, B. subtilis, S. aureus. Updated 12/2016.