Back to search

Peptide record

TPDB21751

Antibacterial Antifungal standard
128 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21751
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb
standard
No
A 128-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, and CAFPdb, with an available 3D structural model.
Sequence
KESRAKKFQRQHMDSDSSPSSSSTYCNQMMRRRNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRYPNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C610H966N192O198S13
W
S
14574.33
8.70
23
12
33
+6
2.92
-0.916
41.02
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
7950
0.55
53
Residue Composition
number
4
A
10
R
9
N
6
D
8
C
6
E
7
Q
5
G
5
H
3
I
2
L
8
K
5
M
4
F
7
P
16
S
8
T
0
W
5
Y
10
V
Amino Acid Distribution
A: 4 R: 10 N: 9 D: 6 C: 8 E: 6 Q: 7 G: 5 H: 5 I: 3 L: 2 K: 8 M: 5 F: 4 P: 7 S: 16 T: 8 W: 0 Y: 5 V: 10
Chemical Descriptors
128 reviewed residue count
C610H966N192O198S13 sequence-only estimate (linear, free termini)
14574.33 sequence-only estimate (linear, free termini)
8.70 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
2.92 sequence-only estimate (linear, free termini)
-0.916 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against E. coli strains, C. albicans, and C. glabrata.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

CAFPdb Antifungipept

Other

Active against E. coli strains, C. albicans, and C. glabrata.