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Peptide record

TPDB21746

Antibacterial Anticancer Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB21746
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KFAKFAKKFAKFAKGGPQQFFGLM
Physicochemical Analysis
C134H200N32O27S1
RNDCEHISTWYV
KF
2723.32
11.21
6
0
12
+6
-0.67
-0.146
32.92
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
0
I
1
L
6
K
1
M
6
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 0 L: 1 K: 6 M: 1 F: 6 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C134H200N32O27S1
2723.32
11.21
+6
-0.67
-0.146
Evidence Records 2 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
250 µM
Hemolytic Cytotoxic
<10% Hemolysis | 250 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Enhanced cell selectivity of hybrid peptides with potential antimicrobial activity and immunomodulatory effect. | Biochim Biophys Acta | 2020
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
500 µM
Hemolytic Cytotoxic
10% Hemolysis | 500 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Enhanced cell selectivity of hybrid peptides with potential antimicrobial activity and immunomodulatory effect. | Biochim Biophys Acta | 2020