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Peptide record

TPDB21692

Antibacterial Antifungal standard
52 amino acids
Basic Information
3D PDB MODEL
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TPDB21692
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 52-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
KACPRNCDTDIAYMVCPSSGERIIRKVCTNCCAAQKGCKLFRSNGSIKCTGT
Physicochemical Analysis
C229H387N73O72S9
HW
C
5603.58
8.74
9
3
14
+6
9.97
-0.231
56.35
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1990
35.51
21
Residue Composition
number
4
A
4
R
3
N
2
D
8
C
1
E
1
Q
4
G
0
H
4
I
1
L
5
K
1
M
1
F
2
P
4
S
4
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 4 R: 4 N: 3 D: 2 C: 8 E: 1 Q: 1 G: 4 H: 0 I: 4 L: 1 K: 5 M: 1 F: 1 P: 2 S: 4 T: 4 W: 0 Y: 1 V: 2
Chemical Descriptors
52
C229H387N73O72S9
5603.58
8.74
+6
9.97
-0.231
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active again yeasts S. cerevisiae, C. albicans, C. tropicalis and K. marxianus. It also inhibited the alpha-amylase activities from C. maculatus and human saliva in vitro. This peptide S3 has an identical sequence to PSI-1.2 initially identified as serine proteinase inhibitor that inhibits both trypsin and chymotrypsin ( Antcheva N et al., 2001 ). Also refer to UniProKB: P83241 .
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active again yeasts S. cerevisiae, C. albicans, C. tropicalis and K. marxianus. It also inhibited the alpha-amylase activities from C. maculatus and human saliva in vitro. This peptide S3 has an identical sequence to PSI-1.2 initially identified as serine proteinase inhibitor that inhibits both trypsin and chymotrypsin ( Antcheva N et al., 2001 ). Also refer to UniProKB: P83241 .