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Peptide record

TPDB21690

Z2 Antibacterial Anticancer standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB21690
Z2
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia AntiCP 2.0 CancerPPD 2.0 SATPdb dbACP iACP-DRLF
standard
No
A 21-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia, AntiCP 2.0, CancerPPD 2.0, and other sources, with an available 3D structural model.
Sequence
KAAKKWAKAWKKAAKAWKKAA
Physicochemical Analysis
C114H185N33O22
RNDCEQGHILMFPSTYV
AK
2369.93
11.41
9
0
12
+9
1.83
-1.029
42.86
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
16500
696.22
0
Residue Composition
number
9
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
9
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 9 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 9 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
21
C114H185N33O22
2369.93
11.41
+9
1.83
-1.029
Free
L
Linear
Free
Anticancer
Synthetic
Evidence Records 3 records
Evidence 1 Activity

Activity

EC50
EC50 >211 µM
Anticancer
211 µM

Target

Skin Cancer
Meth A
Skin

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.
Evidence 2 Activity

Activity

EC50
EC50 =173 µM
Anticancer
173 µM

Target

Breast Cancer
MT-1
Breast

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011
Evidence 3 Activity

Activity

EC50
EC50 >211 µM
Anticancer
211 µM

Target

Colon Cancer
HT-29
Colon

Assay & Model

MTT/MTS assay
Not Available

Source & Reference

CancerPPD 2.0 dbACP SATPdb
CancerPPD2
2011