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Peptide record

TPDB21676

Antibacterial Antifungal standard
58 amino acids
Basic Information
3D PDB MODEL
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TPDB21676
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 58-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
IVWIAKQFGVHLTTSLTQKALDLLSAGSSLGTVAAAVLGVTLPAWAVAAAGALGGTAA
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C256H418N66O73
RNCEMY
A
5588.53
9.88
3
1
34
+1
-0.92
1.057
128.10
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
11000
1.97
12
Residue Composition
number
14
A
0
R
0
N
1
D
0
C
0
E
2
Q
7
G
1
H
2
I
9
L
2
K
0
M
1
F
1
P
4
S
6
T
2
W
0
Y
6
V
Amino Acid Distribution
A: 14 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 2 G: 7 H: 1 I: 2 L: 9 K: 2 M: 0 F: 1 P: 1 S: 4 T: 6 W: 2 Y: 0 V: 6
Chemical Descriptors
58 reviewed residue count
C256H418N66O73 sequence-only estimate (linear, free termini)
5588.53 sequence-only estimate (linear, free termini)
9.88 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
-0.92 sequence-only estimate (linear, free termini)
1.057 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against A. acidoterrestris sp1, L. lactis HP, L. lactis KH, L. lactis MG1363, L. lactis RT28, L. lactis NZ9000, L. bulgaricus UCC, and P. inopinatus 1011.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against A. acidoterrestris sp1, L. lactis HP, L. lactis KH, L. lactis MG1363, L. lactis RT28, L. lactis NZ9000, L. bulgaricus UCC, and P. inopinatus 1011.