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Peptide record

TPDB21645

Antibacterial Antiparasitic Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB21645
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IWGLIAHGVAHVGSLIHGLVNG
Physicochemical Analysis
C103H162N30O25
RDCEQKMFPTY
G
2220.61
8.09
3
0
12
+0
-1.11
1.105
155.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
247.68
2
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
5
G
3
H
3
I
3
L
0
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 5 H: 3 I: 3 L: 3 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
22
C103H162N30O25
2220.61
8.09
+0
-1.11
1.105
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

All tested bacteria and yeast were resistant to synthetic So-pis at the tested concentrations. However, it showed activity against C. irritans trophonts and theronts (killed 20% at 12 uM in 60 min, 83% at 24 uM in 30 min, and 100% at 48 uM or 96 uM in 15 min). MOA: cell lysis and cause leak.
Evidence 2 Activity

Activity

Antiparasitic

Source & Reference

NA

Other

All tested bacteria and yeast were resistant to synthetic So-pis at the tested concentrations. However, it showed activity against C. irritans trophonts and theronts (killed 20% at 12 uM in 60 min, 83% at 24 uM in 30 min, and 100% at 48 uM or 96 uM in 15 min). MOA: cell lysis and cause leak.