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Peptide record

TPDB21622

Antibacterial Anticancer Antiviral Toxicity modified_plain modified
12 amino acids
Basic Information
3D PDB MODEL
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TPDB21622
Antibacterial Anticancer Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia dbAMP 3.0
modified_plain
Yes
A 12-aa modified multi-activity (Antibacterial, Anticancer, Antiviral, and other sources) peptide sequence curated from Peptipedia and dbAMP 3.0, with an available 3D structural model.
Modified, details unspecified
Sequence
ITFXDLLXYYGP
Physicochemical Analysis
C60H84N10O16
ARNCEQHKMSWV
LY
1201.38
3.10
0
1
6
-1
-2.61
0.508
97.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
2980
248.05
3
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
0
K
0
M
1
F
1
P
0
S
1
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 0 M: 0 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 2 V: 0
Chemical Descriptors
12
C60H84N10O16
1201.38
3.10
-1
-2.61
0.508
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>300 µM
Cytotoxic
50% Cytotoxicity | >300 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
A cell-penetrating helical peptide as a potential HIV-1 inhibitor. | J Mol Biol | 2008