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Peptide record

TPDB21617

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB21617
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
ITRYLDKILRILRKYLKA
Physicochemical Analysis
C107H186N30O24
NCEQGHMFPSWV
L
2276.84
10.94
6
1
10
+5
1.55
-0.083
157.22
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
2980
130.88
3
Residue Composition
number
1
A
3
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
3
I
4
L
3
K
0
M
0
F
0
P
0
S
1
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 4 K: 3 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 2 V: 0
Chemical Descriptors
18
C107H186N30O24
2276.84
10.94
+5
1.55
-0.083
Evidence Records 3 records
Evidence 1 Activity

Activity

0% Cell death
Toxicity
8.75 µM
Cytotoxic
0% Cell death | 8.75 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Development of a novel anti-biofilm peptide derived from profilin of Spodoptera frugiperda | Biofouling | 2020
Evidence 2 Activity

Activity

25% Cell death
Toxicity
17.5 µM
Cytotoxic
25% Cell death | 17.5 | µM | target cell: Human fibroblasts MRC-5

Target

Human fibroblasts MRC-5

Source & Reference

NA
DBAASP
Development of a novel anti-biofilm peptide derived from profilin of Spodoptera frugiperda | Biofouling | 2020
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
<225 µM
Hemolytic Cytotoxic
0% Hemolysis | <225 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Development of a novel anti-biofilm peptide derived from profilin of Spodoptera frugiperda | Biofouling | 2020