Peptide record

TPDB21614

Antibacterial Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB21614
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 23-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
ISIKEALEHSFFHTVPRKWCKKH
Physicochemical Analysis
C131H201N37O31S1
NDQGMY
K
2822.33
10.16
8
2
8
+3
6.91
-0.635
67.83
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
194.87
4
Residue Composition
number
1
A
1
R
0
N
0
D
1
C
2
E
0
Q
0
G
3
H
2
I
1
L
4
K
0
M
2
F
1
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 1 E: 2 Q: 0 G: 0 H: 3 I: 2 L: 1 K: 4 M: 0 F: 2 P: 1 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C131H201N37O31S1
2822.33
10.16
+3
6.91
-0.635
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 64 ug/ml), S.enteritidis (MIC 128 ug/ml), and S.aureus ATCC 29213 (MIC 128 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.enteritidis

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 64 ug/ml), S.enteritidis (MIC 128 ug/ml), and S.aureus ATCC 29213 (MIC 128 ug/ml).
Evidence 3 Activity

Activity

MIC
Antibacterial
128 µg/mL

Target

S.aureus ATCC 29213

Source & Reference

NA

Other

Active against E. coli ATCC 25922 (MIC 64 ug/ml), S.enteritidis (MIC 128 ug/ml), and S.aureus ATCC 29213 (MIC 128 ug/ml).
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
>128 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | >128 | µg/mL | target cell: Pig erythrocytes

Target

Pig erythrocytes

Source & Reference

NA
DBAASP