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Peptide record

TPDB21574

Antibacterial Anticancer Toxicity modified_plain modified
28 amino acids
Basic Information
3D PDB MODEL
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TPDB21574
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 28-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
IPCGESCVWIPCISGXFGCSCKDKVCYS
Physicochemical Analysis
C124H190N30O37S6
ARNQHLMT
C
2885.41
5.97
2
2
8
-0
0.53
0.539
62.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
7365
255.25
11
Residue Composition
number
0
A
0
R
0
N
1
D
6
C
1
E
0
Q
3
G
0
H
3
I
0
L
2
K
0
M
1
F
2
P
4
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 3 L: 0 K: 2 M: 0 F: 1 P: 2 S: 4 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
28
C124H190N30O37S6
2885.41
5.97
-0
0.53
0.539
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>25 µM
Hemolytic Cytotoxic
50% Hemolysis | >25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel cyclotides and uncyclotides with highly shortened precursors from Chassalia chartacea and effects of methionine oxidation on bioactivities. | J Biol Chem | 2012
Evidence 2 Activity

Activity

HD50
Toxicity
25 µM
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: HD50>25 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
J Biol Chem. 2012 May 18 287(21):17598-17607.