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Peptide record

TPDB21555

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB21555
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb ToxinPred 3.0
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and ToxinPred 3.0, with an available 3D structural model.
Sequence
INLRAIAAFAKKLL
Physicochemical Analysis
C73H128N20O16
DCEQGHMPSTWYV
A
1541.94
11.64
3
0
10
+3
-0.90
1.043
167.86
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
4
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
3
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 3 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C73H128N20O16
1541.94
11.64
+3
-0.90
1.043
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against S. aureus (MIC 32 ug/ml) and E. coli (MIC 32 ug/ml). Reg. 7/2021
Evidence 2 Activity

Activity

MIC
Antibacterial
32 µg/mL

Target

Escherichia coli

Source & Reference

NA

Other

Active against S. aureus (MIC 32 ug/ml) and E. coli (MIC 32 ug/ml). Reg. 7/2021
Evidence 3 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

Staphylococcus aureus

Source & Reference

CAFPdb

Other

Active against S. aureus (MIC 32 ug/ml) and E. coli (MIC 32 ug/ml). Reg. 7/2021
Evidence 4 Activity

Activity

MIC
Antifungal
32 µg/mL

Target

Escherichia coli

Source & Reference

CAFPdb

Other

Active against S. aureus (MIC 32 ug/ml) and E. coli (MIC 32 ug/ml). Reg. 7/2021
Evidence 5 Activity

Activity

3.548±0.008% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
3.548±0.008% Hemolysis | 256 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Functional characterization, antimicrobial effects, and potential antibacterial mechanisms of new mastoparan peptides from hornet venom (Vespa ducalis, Vespa mandarinia, and Vespa affinis). | Toxicon | 2021