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Peptide record

TPDB21552

Antibacterial Antifungal Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB21552
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
INWLHLGHMVIDAL
Physicochemical Analysis
C76H118N20O18S1
RCEQKFPSTY
L
1631.96
6.01
2
1
9
-1
-0.90
0.971
167.14
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
337.02
1
Residue Composition
number
1
A
0
R
1
N
1
D
0
C
0
E
0
Q
1
G
2
H
2
I
3
L
0
K
1
M
0
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 2 I: 2 L: 3 K: 0 M: 1 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
14
C76H118N20O18S1
1631.96
6.01
-1
-0.90
0.971
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
10% Hemolysis | 128 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
The effects of incorporation of the counterparts and mimics of l-lysine on the antimicrobial activity, hemolytic activity, cytotoxicity and tryptic stability of antimicrobial peptide polybia-MPII. | Amino Acids | 2022
Evidence 2 Activity

Activity

70% Cytotoxicity
Toxicity
128 µM
Cytotoxic
70% Cytotoxicity | 128 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
The effects of incorporation of the counterparts and mimics of l-lysine on the antimicrobial activity, hemolytic activity, cytotoxicity and tryptic stability of antimicrobial peptide polybia-MPII. | Amino Acids | 2022