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Peptide record

TPDB21516

Antibacterial Antifungal Toxicity modified_plain modified
13 amino acids
Basic Information
3D PDB MODEL
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TPDB21516
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 13-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
ILPXKXPXXPXRR
Physicochemical Analysis
C45H81N15O9
ANDCEQGHMFSTWYV
P
976.23
12.41
3
0
2
+3
3.09
-0.723
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C45H81N15O9
976.23
12.41
+3
3.09
-0.723
Evidence Records 10 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
103.3 µM
Hemolytic Cytotoxic
50% Hemolysis | 103.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
70.8±10.21 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 70.8±10.21 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 4 Activity

Activity

50% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
120.8±10.21 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 120.8±10.21 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 6 Activity

Activity

50% Hemolysis
Toxicity
15±10.95 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 15±10.95 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 7 Activity

Activity

50% Hemolysis
Toxicity
37.5±13.69 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 37.5±13.69 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 8 Activity

Activity

50% Hemolysis
Toxicity
18.3±10.33 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 18.3±10.33 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 9 Activity

Activity

50% Hemolysis
Toxicity
21.7±8.16 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 21.7±8.16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 10 Activity

Activity

50% Hemolysis
Toxicity
5 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020