Back to search

Peptide record

TPDB21480

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21480
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia and PD_Hemolysis, with an available 3D structural model.
Sequence
ILPWKWPCWPCRR
Physicochemical Analysis
C84H121N23O14S2
ANDEQGHMFSTYV
PW
1741.15
10.12
3
0
5
+3
-2.94
-0.546
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
16625
954.83
2
Residue Composition
number
0
A
2
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
3
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 3 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
13
C84H121N23O14S2
1741.15
10.12
+3
-2.94
-0.546
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
191.7±20.41 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 191.7±20.41 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
37.5±13.69 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 37.5±13.69 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis