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Peptide record

TPDB21475

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB21475
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia and PD_Hemolysis, with an available 3D structural model.
Sequence
ILPWKWCWWCWRR
Physicochemical Analysis
C96H127N25O14S2
ANDEQGHMFSTYV
W
1919.34
10.12
3
0
7
+3
-7.54
-0.438
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
27625
1439.29
2
Residue Composition
number
0
A
2
R
0
N
0
D
2
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
1
P
0
S
0
T
5
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 5 Y: 0 V: 0
Chemical Descriptors
13
C96H127N25O14S2
1919.34
10.12
+3
-7.54
-0.438
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
116.7±12.91 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 116.7±12.91 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
62.5±13.69 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 62.5±13.69 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis