Back to search

Peptide record

TPDB21455

Antibacterial Antifungal Toxicity modified_plain modified
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21455
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 13-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
ILPFKYPFXPFRR
Physicochemical Analysis
C81H117N19O14
ANDCEQGHMSTWV
FP
1580.94
11.39
3
0
6
+3
-1.24
-0.177
60.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
94.25
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
3
F
3
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 3 P: 3 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
13
C81H117N19O14
1580.94
11.39
+3
-1.24
-0.177
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Indolicidin analogs with broad-spectrum antimicrobial activity and low hemolytic activity | Peptides | 2020