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Peptide record

TPDB21386

Antibacterial Antiviral Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB21386
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
ILGPVLGLVSRTLRRVLGIL
Physicochemical Analysis
C99H181N29O23
ANDCEQHKMFWY
L
2145.71
12.70
3
0
11
+3
-0.59
1.330
199.50
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
2
I
6
L
0
K
0
M
0
F
1
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 6 K: 0 M: 0 F: 0 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
20
C99H181N29O23
2145.71
12.70
+3
-0.59
1.330
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

inhibited Human Immunodeficiency Virus Type 1 HIV-1 (EC50 2.2 uM).
Evidence 2 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAVP 2.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
inhibited Human Immunodeficiency Virus Type 1 HIV-1 (EC50 2.2 uM).
Evidence 3 Activity

Activity

50% Cell death
Toxicity
8.7 µM
Cytotoxic
50% Cell death | 8.7 | µM | target cell: CEM-SS cells

Target

CEM-SS cells

Source & Reference

NA
DBAASP
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database. | Antimicrob Agents Chemother | 2010
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.20086159]CEM-SS cells:50% Cell death at 8.7 µM.

Source & Reference

NA
DRAMP
Antimicrob Agents Chemother. 2010 Mar 54(3):1343-6.