TPDB21347

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 3-6 µM

Target

Target Organism S. flexneri

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- S. flexneri (MIC 3-6 uM), P. fluorescens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MI

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 6-12 µM

Target

Target Organism Pseudomonas fluorescens

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- S. flexneri (MIC 3-6 uM), P. fluorescens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.5-3 um

Target

Target Organism Pseudomonas stutzeri

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- S. flexneri (MIC 3-6 uM), P. fluorescens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19124 or QZ19125 (MIC 6-12 uM)

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 3-12 µM

Target

Target Organism Escherichia coli QZ18109 or QZ18110

Source & Reference

Database Source NA

Other

Evidence Text

Gram- S. flexneri (MIC 3-6 uM), P. fluorescens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19124 or QZ19125 (MIC 6-12 uM), A. baumannii QZ18050A or QZ18055 (MIC 1.

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 6-12 µM

Target

Target Organism Pseudomonas aeruginosa QZ19124 or QZ19125

Source & Reference

Database Source NA

Other

Evidence Text

cens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19124 or QZ19125 (MIC 6-12 uM), A. baumannii QZ18050A or QZ18055 (MIC 1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 1.5-3 µM

Target

Target Organism A. baumannii QZ18050A or QZ18055

Source & Reference

Database Source NA

Other

Evidence Text

E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19124 or QZ19125 (MIC 6-12 uM), A. baumannii QZ18050A or QZ18055 (MIC 1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 6-24 µM

Target

Target Organism Klebsiella pneumoniae QZ18106 or QZ18107

Source & Reference

Database Source NA

Other

Evidence Text

ginosa QZ19124 or QZ19125 (MIC 6-12 uM), A. baumannii QZ18050A or QZ18055 (MIC 1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 24-48 µM

Target

Target Organism A. hydrophila

Source & Reference

Database Source NA

Other

Evidence Text

annii QZ18050A or QZ18055 (MIC 1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C

Evidence 9 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 24-48 µM

Target

Target Organism E. tarda

Source & Reference

Database Source NA

Other

Evidence Text

1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM)

Evidence 10 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 24-48 µM

Target

Target Organism A. sobria

Source & Reference

Database Source NA

Other

Evidence Text

QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM

Evidence 11 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 6-12 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source NA

Other

Evidence Text

), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM)

Evidence 12 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 3-6 µM

Target

Target Organism C. glutamicum

Source & Reference

Database Source NA

Other

Evidence Text

), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM) and fungi C. neoformans (MIC

Evidence 13 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 6-12 µM

Target

Target Organism B. subtilis

Source & Reference

Database Source NA

Other

Evidence Text

A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM) and fungi C. neoformans (MIC 12-24 uM).

Evidence 14 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 6-12 µM

Target

Target Organism E. faecium QZ18080

Source & Reference

Database Source NA

Other

Evidence Text

ram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM) and fungi C. neoformans (MIC 12-24 uM).

Evidence 15 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 12-24 µM

Target

Target Organism C. neoformans

Source & Reference

Database Source NA

Other

Evidence Text

micum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM) and fungi C. neoformans (MIC 12-24 uM).

Evidence 16 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 3-6 µM

Target

Target Organism S. flexneri

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- S. flexneri (MIC 3-6 uM), P. fluorescens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MI

Evidence 17 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 6-12 µM

Target

Target Organism Pseudomonas fluorescens

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- S. flexneri (MIC 3-6 uM), P. fluorescens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19

Evidence 18 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.5-3 um

Target

Target Organism Pseudomonas stutzeri

Source & Reference

Database Source NA

Other

Evidence Text

active against Gram- S. flexneri (MIC 3-6 uM), P. fluorescens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19124 or QZ19125 (MIC 6-12 uM)

Evidence 19 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 3-12 µM

Target

Target Organism Escherichia coli QZ18109 or QZ18110

Source & Reference

Database Source NA

Other

Evidence Text

Gram- S. flexneri (MIC 3-6 uM), P. fluorescens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19124 or QZ19125 (MIC 6-12 uM), A. baumannii QZ18050A or QZ18055 (MIC 1.

Evidence 20 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 6-12 µM

Target

Target Organism Pseudomonas aeruginosa QZ19124 or QZ19125

Source & Reference

Database Source NA

Other

Evidence Text

cens (MIC 6-12 uM), P. stutzeri (MIC 1.5-3 um), E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19124 or QZ19125 (MIC 6-12 uM), A. baumannii QZ18050A or QZ18055 (MIC 1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6

Evidence 21 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 1.5-3 µM

Target

Target Organism A. baumannii QZ18050A or QZ18055

Source & Reference

Database Source NA

Other

Evidence Text

E. coli QZ18109 or QZ18110 (MIC 3-12 uM), P. aeruginosa QZ19124 or QZ19125 (MIC 6-12 uM), A. baumannii QZ18050A or QZ18055 (MIC 1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (

Evidence 22 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 6-24 µM

Target

Target Organism Klebsiella pneumoniae QZ18106 or QZ18107

Source & Reference

Database Source NA

Other

Evidence Text

ginosa QZ19124 or QZ19125 (MIC 6-12 uM), A. baumannii QZ18050A or QZ18055 (MIC 1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S

Evidence 23 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 24-48 µM

Target

Target Organism A. hydrophila

Source & Reference

Database Source NA

Other

Evidence Text

annii QZ18050A or QZ18055 (MIC 1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C

Evidence 24 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 24-48 µM

Target

Target Organism E. tarda

Source & Reference

Database Source NA

Other

Evidence Text

1.5-3 uM), K. pneumoniae QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM)

Evidence 25 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 24-48 µM

Target

Target Organism A. sobria

Source & Reference

Database Source NA

Other

Evidence Text

QZ18106 or QZ18107 (MIC 6-24 uM), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM

Evidence 26 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 6-12 µM

Target

Target Organism Staphylococcus epidermidis

Source & Reference

Database Source NA

Other

Evidence Text

), A. hydrophila (MIC 24-48 uM), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM)

Evidence 27 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 3-6 µM

Target

Target Organism C. glutamicum

Source & Reference

Database Source NA

Other

Evidence Text

), E. tarda (MIC 24-48 uM), A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM) and fungi C. neoformans (MIC

Evidence 28 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 6-12 µM

Target

Target Organism B. subtilis

Source & Reference

Database Source NA

Other

Evidence Text

A. sobria (MIC 24-48 uM), Gram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM) and fungi C. neoformans (MIC 12-24 uM).

Evidence 29 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 6-12 µM

Target

Target Organism E. faecium QZ18080

Source & Reference

Database Source NA

Other

Evidence Text

ram+ S. epidermidis (MIC 6-12 uM), C. glutamicum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM) and fungi C. neoformans (MIC 12-24 uM).

Evidence 30 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 12-24 µM

Target

Target Organism C. neoformans

Source & Reference

Database Source NA

Other

Evidence Text

micum (MIC 3-6 uM), B. subtilis (MIC 6-12 uM), E. faecium QZ18080 (MIC 6-12 uM) and fungi C. neoformans (MIC 12-24 uM).

Evidence 31 Activity

Activity

Detail Source Activity Toxicity

Toxicity Type Cytotoxic

Toxicity Raw

NA | target cell: Human embryonic kidney HEK293T cells

Target

Target Cell Human embryonic kidney HEK293T cells

Source & Reference

Database Source NA

Source Database DBAASP

Reference

The Antimicrobial Peptide LJ-hep2 from Lateolabrax japonicus Exerting Activities against Multiple Pathogenic Bacteria and Immune Protection In Vivo. | Mar Drugs | 2022

Evidence 32 Activity

Activity

Detail Source Activity Toxicity

Toxicity Type Cytotoxic

Toxicity Raw

NA | target cell: Epithelioma papulosum cyprini cells (EPC)

Target

Target Cell Epithelioma papulosum cyprini cells (EPC)

Source & Reference

Database Source NA

Source Database DBAASP

Reference

The Antimicrobial Peptide LJ-hep2 from Lateolabrax japonicus Exerting Activities against Multiple Pathogenic Bacteria and Immune Protection In Vivo. | Mar Drugs | 2022

Evidence 33 Activity

Activity

Detail Source Activity Toxicity

Toxicity Type Cytotoxic

Toxicity Raw

NA | target cell: Zebrafish embryos

Target

Target Cell Zebrafish embryos

Source & Reference

Database Source NA

Source Database DBAASP

Reference

The Antimicrobial Peptide LJ-hep2 from Lateolabrax japonicus Exerting Activities against Multiple Pathogenic Bacteria and Immune Protection In Vivo. | Mar Drugs | 2022