Back to search

Peptide record

TPDB21324

Antibacterial Anticancer Toxicity modified_plain modified
29 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21324
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 29-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
IKLXKEXKKXLKKVLKGXIKGXIAVAKMV
Physicochemical Analysis
C125H235N33O27S1
RNDCQHFPSTWY
K
2664.51
11.06
9
1
12
+8
7.98
0.124
117.59
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
3
I
3
L
9
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 3 L: 3 K: 9 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
29
C125H235N33O27S1
2664.51
11.06
+8
7.98
0.124
Evidence Records 2 records
Evidence 1 Activity

Activity

65% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
65% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improving Selectivity, Proteolytic Stability, and Antitumor Activity of Hymenochirin-1B: A Novel Glycosylated Staple Strategy. | ACS Chem Biol | 2019
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
ACS Chem Biol. 2019 Mar 15 14(3):516-525.