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Peptide record

TPDB21314

Antibacterial Anticancer Toxicity modified_plain modified
29 amino acids
Basic Information
3D PDB MODEL
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TPDB21314
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 29-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
IKLSKKTKKNLKKVLKGXIKGXIAVAKMV
Physicochemical Analysis
C137H258N38O31S1
RDCEQHFPWY
K
2965.85
11.46
10
0
12
+10
7.64
-0.062
117.59
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
3
L
10
K
1
M
0
F
0
P
1
S
1
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 3 K: 10 M: 1 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 3
Chemical Descriptors
29
C137H258N38O31S1
2965.85
11.46
+10
7.64
-0.062
Evidence Records 1 records
Evidence 1 Activity

Activity

90% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
90% Hemolysis | 20 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Improving Selectivity, Proteolytic Stability, and Antitumor Activity of Hymenochirin-1B: A Novel Glycosylated Staple Strategy. | ACS Chem Biol | 2019