Back to search

Peptide record

TPDB21290

Antibacterial standard
44 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21290
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 44-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IINTLQRYYCRIRSGRCALLSCLPKEEQIGRCSSTGRKCCRRKK
Physicochemical Analysis
C214H373N75O60S6
DHMFWV
R
5149.14
10.40
12
2
11
+10
10.37
-0.661
73.18
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
3355
65.16
17
Residue Composition
number
1
A
8
R
1
N
0
D
6
C
2
E
2
Q
3
G
0
H
4
I
4
L
4
K
0
M
0
F
1
P
4
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 8 N: 1 D: 0 C: 6 E: 2 Q: 2 G: 3 H: 0 I: 4 L: 4 K: 4 M: 0 F: 0 P: 1 S: 4 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
44
C214H373N75O60S6
5149.14
10.40
+10
10.37
-0.661
Evidence Records 1 records
Evidence 1 Activity

Activity

MIC
Antibacterial
8 µM

Target

E. faecium clinical isolate

Source & Reference

NA

Other

P-aeruginosa ATCC 27853, P-hauseri ATCC 13315, E-faecalis clinical isolate (MIC >64 uM), E. faecium clinical isolate (MIC 8 uM). The peptide can kill all the tested Gram+ and - bacterial strains in a minimal medium, i