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Peptide record

TPDB21254

Antibacterial Antifungal standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB21254
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 51-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
IGGALGNALAGLGNGLKQWNTTGFSEYNIGGGKVNNGKAPTSIPAYNPYGH
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C228H347N65O70
RDCM
G
5118.66
9.76
4
1
18
+2
0.61
-0.388
69.02
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
9970
1.95
16
Residue Composition
number
5
A
0
R
7
N
0
D
0
C
1
E
1
Q
12
G
1
H
3
I
4
L
3
K
0
M
1
F
3
P
2
S
3
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 5 R: 0 N: 7 D: 0 C: 0 E: 1 Q: 1 G: 12 H: 1 I: 3 L: 4 K: 3 M: 0 F: 1 P: 3 S: 2 T: 3 W: 1 Y: 3 V: 1
Chemical Descriptors
51 reviewed residue count
C228H347N65O70 sequence-only estimate (linear, free termini)
5118.66 sequence-only estimate (linear, free termini)
9.76 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
0.61 sequence-only estimate (linear, free termini)
-0.388 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against L. garvieae IBB3403 and IBB66 only.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against L. garvieae IBB3403 and IBB66 only.