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Peptide record

TPDB21253

Antibacterial standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB21253
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 13-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IFKAIWSGINRLF
Physicochemical Analysis
C77H117N19O16
DCEQHMPTYV
I
1564.89
11.49
2
0
8
+2
-3.41
0.823
127.69
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
351.46
2
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
3
I
1
L
1
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 3 L: 1 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C77H117N19O16
1564.89
11.49
+2
-3.41
0.823
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.25-12.5 µg/mL

Target

Staphylococcus aureus and 4 MRSA strains

Source & Reference

NA

Other

active against S. aureus 5 strains and 4 MRSA strains (MIC 6.25-12.5 ug/ml), S. epidermidis 2 strains (MIC 25 ug/ml), M. luteus AB93113 (MIC 50 ug/ml), B. subtilis A
Evidence 2 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

active against S. aureus 5 strains and 4 MRSA strains (MIC 6.25-12.5 ug/ml), S. epidermidis 2 strains (MIC 25 ug/ml), M. luteus AB93113 (MIC 50 ug/ml), B. subtilis ATCC6051 (MIC 25 ug/ml) but not E.coli ATC
Evidence 3 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

M. luteus AB93113

Source & Reference

NA

Other

trains and 4 MRSA strains (MIC 6.25-12.5 ug/ml), S. epidermidis 2 strains (MIC 25 ug/ml), M. luteus AB93113 (MIC 50 ug/ml), B. subtilis ATCC6051 (MIC 25 ug/ml) but not E.coli ATCC8739 or ATCC25922 (MIC >100 ug/ml
Evidence 4 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

B. subtilis ATCC6051

Source & Reference

NA

Other

5-12.5 ug/ml), S. epidermidis 2 strains (MIC 25 ug/ml), M. luteus AB93113 (MIC 50 ug/ml), B. subtilis ATCC6051 (MIC 25 ug/ml) but not E.coli ATCC8739 or ATCC25922 (MIC >100 ug/ml). bacteriostatic not killing.
Evidence 5 Activity

Activity

MIC
Antibacterial
>100 µg/mL

Target

E.coli ATCC8739 or ATCC25922

Source & Reference

NA

Other

25 ug/ml), M. luteus AB93113 (MIC 50 ug/ml), B. subtilis ATCC6051 (MIC 25 ug/ml) but not E.coli ATCC8739 or ATCC25922 (MIC >100 ug/ml). bacteriostatic not killing.