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Peptide record

TPDB21250

Antibacterial Anticancer Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB21250
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IFPYPIP
Physicochemical Analysis
C45H63N7O9
ARNDCEQGHLKMSTWV
P
846.04
5.94
0
0
4
-0
-1.34
0.814
111.43
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
1490
176.12
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
1
F
3
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 1 P: 3 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
7
C45H63N7O9
846.04
5.94
-0
-1.34
0.814
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
Toxicity
2600 µM
Cytotoxic
IC50 | 2600 | µM | target cell: Murine macrophage cells J774A.1

Target

Murine macrophage cells J774A.1

Source & Reference

NA
DBAASP
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 | Tetrahedron | 2003
Evidence 2 Activity

Activity

IC50
Toxicity
3900 µM
Cytotoxic
IC50 | 3900 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Synthesis, structural aspects and cytotoxicity of the natural cyclopeptides yunnanins A, C and phakellistatins 1, 10 | Tetrahedron | 2003