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Peptide record

TPDB21241

Antibacterial Antifungal standard
13 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB21241
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse CAFPdb
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, and CAFPdb, with an available 3D structural model.
Sequence
IFGKIWEGIKSLF
Physicochemical Analysis
C77H116N16O17
ARNDCQHMPTYV
I
1537.87
9.88
2
1
7
+1
-1.45
0.700
120.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
357.64
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
2
G
0
H
3
I
1
L
2
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 2 H: 0 I: 3 L: 1 K: 2 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
13
C77H116N16O17
1537.87
9.88
+1
-1.45
0.700
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.7 µM

Target

Staphylococcus aureus ATCC 25293

Source & Reference

NA

Other

Inhibited Gram+ S. aureus ATCC 25293 (MIC 0.7 uM), S. aureus ATCC 6538 (MIC 3.3 uM), S. saprophyticus clincal strain (MIC 0.7 uM), B. thuri
Evidence 2 Activity

Activity

MIC
Antibacterial
3.3 µM

Target

Staphylococcus aureus ATCC 6538

Source & Reference

NA

Other

Inhibited Gram+ S. aureus ATCC 25293 (MIC 0.7 uM), S. aureus ATCC 6538 (MIC 3.3 uM), S. saprophyticus clincal strain (MIC 0.7 uM), B. thuringensis (MIC 16.6 uM), B. subtilis
Evidence 3 Activity

Activity

MIC
Antibacterial
0.7 µM

Target

S. saprophyticus clincal strain

Source & Reference

NA

Other

Inhibited Gram+ S. aureus ATCC 25293 (MIC 0.7 uM), S. aureus ATCC 6538 (MIC 3.3 uM), S. saprophyticus clincal strain (MIC 0.7 uM), B. thuringensis (MIC 16.6 uM), B. subtilis CCT 2471 (6.6 uM), Gram- P.aeroginosa ATCC 15
Evidence 4 Activity

Activity

MIC
Antibacterial
16.6 µM

Target

B. thuringensis

Source & Reference

NA

Other

0.7 uM), S. aureus ATCC 6538 (MIC 3.3 uM), S. saprophyticus clincal strain (MIC 0.7 uM), B. thuringensis (MIC 16.6 uM), B. subtilis CCT 2471 (6.6 uM), Gram- P.aeroginosa ATCC 15442 (MIC>150 uM), P. aeroginosa
Evidence 5 Activity

Activity

MIC
Antibacterial
>150 µM

Target

P.aeroginosa ATCC 15442

Source & Reference

NA

Other

strain (MIC 0.7 uM), B. thuringensis (MIC 16.6 uM), B. subtilis CCT 2471 (6.6 uM), Gram- P.aeroginosa ATCC 15442 (MIC>150 uM), P. aeroginosa ATCC 27853 (MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.m
Evidence 6 Activity

Activity

MIC
Antibacterial
66.5 µM

Target

P. aeroginosa ATCC 27853

Source & Reference

NA

Other

(MIC 16.6 uM), B. subtilis CCT 2471 (6.6 uM), Gram- P.aeroginosa ATCC 15442 (MIC>150 uM), P. aeroginosa ATCC 27853 (MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.mirabilis (MIC >150 uM), and C. albicans
Evidence 7 Activity

Activity

MIC
Antibacterial
3.3 µM

Target

Escherichia coli CCT 1371 or ATCC 25922

Source & Reference

NA

Other

uM), Gram- P.aeroginosa ATCC 15442 (MIC>150 uM), P. aeroginosa ATCC 27853 (MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.mirabilis (MIC >150 uM), and C. albicans (MIC 12.5 uM). Causing vesicle release.
Evidence 8 Activity

Activity

MIC
Antibacterial
>150 µM

Target

P.mirabilis

Source & Reference

NA

Other

uM), P. aeroginosa ATCC 27853 (MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.mirabilis (MIC >150 uM), and C. albicans (MIC 12.5 uM). Causing vesicle release.
Evidence 9 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

Candida albicans

Source & Reference

NA

Other

MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.mirabilis (MIC >150 uM), and C. albicans (MIC 12.5 uM). Causing vesicle release.
Evidence 10 Activity

Activity

MIC
Antifungal
0.7 µM

Target

Staphylococcus aureus ATCC 25293

Source & Reference

CAFPdb

Other

Inhibited Gram+ S. aureus ATCC 25293 (MIC 0.7 uM), S. aureus ATCC 6538 (MIC 3.3 uM), S. saprophyticus clincal strain (MIC 0.7 uM), B. thuri
Evidence 11 Activity

Activity

MIC
Antifungal
3.3 µM

Target

Staphylococcus aureus ATCC 6538

Source & Reference

CAFPdb

Other

Inhibited Gram+ S. aureus ATCC 25293 (MIC 0.7 uM), S. aureus ATCC 6538 (MIC 3.3 uM), S. saprophyticus clincal strain (MIC 0.7 uM), B. thuringensis (MIC 16.6 uM), B. subtilis
Evidence 12 Activity

Activity

MIC
Antifungal
0.7 µM

Target

S. saprophyticus clincal strain

Source & Reference

CAFPdb

Other

Inhibited Gram+ S. aureus ATCC 25293 (MIC 0.7 uM), S. aureus ATCC 6538 (MIC 3.3 uM), S. saprophyticus clincal strain (MIC 0.7 uM), B. thuringensis (MIC 16.6 uM), B. subtilis CCT 2471 (6.6 uM), Gram- P.aeroginosa ATCC 15
Evidence 13 Activity

Activity

MIC
Antifungal
16.6 µM

Target

B. thuringensis

Source & Reference

CAFPdb

Other

0.7 uM), S. aureus ATCC 6538 (MIC 3.3 uM), S. saprophyticus clincal strain (MIC 0.7 uM), B. thuringensis (MIC 16.6 uM), B. subtilis CCT 2471 (6.6 uM), Gram- P.aeroginosa ATCC 15442 (MIC>150 uM), P. aeroginosa
Evidence 14 Activity

Activity

MIC
Antifungal
>150 µM

Target

P.aeroginosa ATCC 15442

Source & Reference

CAFPdb

Other

strain (MIC 0.7 uM), B. thuringensis (MIC 16.6 uM), B. subtilis CCT 2471 (6.6 uM), Gram- P.aeroginosa ATCC 15442 (MIC>150 uM), P. aeroginosa ATCC 27853 (MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.m
Evidence 15 Activity

Activity

MIC
Antifungal
66.5 µM

Target

P. aeroginosa ATCC 27853

Source & Reference

CAFPdb

Other

(MIC 16.6 uM), B. subtilis CCT 2471 (6.6 uM), Gram- P.aeroginosa ATCC 15442 (MIC>150 uM), P. aeroginosa ATCC 27853 (MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.mirabilis (MIC >150 uM), and C. albicans
Evidence 16 Activity

Activity

MIC
Antifungal
3.3 µM

Target

Escherichia coli CCT 1371 or ATCC 25922

Source & Reference

CAFPdb

Other

uM), Gram- P.aeroginosa ATCC 15442 (MIC>150 uM), P. aeroginosa ATCC 27853 (MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.mirabilis (MIC >150 uM), and C. albicans (MIC 12.5 uM). Causing vesicle release.
Evidence 17 Activity

Activity

MIC
Antifungal
>150 µM

Target

P.mirabilis

Source & Reference

CAFPdb

Other

uM), P. aeroginosa ATCC 27853 (MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.mirabilis (MIC >150 uM), and C. albicans (MIC 12.5 uM). Causing vesicle release.
Evidence 18 Activity

Activity

MIC
Antifungal
12.5 µM

Target

Candida albicans

Source & Reference

CAFPdb

Other

MIC 66.5 uM), E. coli CCT 1371 or ATCC 25922 (MIC 3.3 uM), P.mirabilis (MIC >150 uM), and C. albicans (MIC 12.5 uM). Causing vesicle release.