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Peptide record

TPDB21232

Antibacterial Anticancer Antiviral Toxicity modified_plain modified
31 amino acids
Basic Information
3D PDB MODEL
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TPDB21232
Antibacterial Anticancer Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 31-aa modified multi-activity (Antibacterial, Anticancer, Antiviral, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
IEPHDWTKNIKDKIDKIIHDFVDKTLPDQGX
Physicochemical Analysis
C161H252N42O49
ARCMSY
D
3560.02
5.27
7
7
9
-2
13.44
-0.968
84.84
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
154.49
4
Residue Composition
number
0
A
0
R
1
N
6
D
0
C
1
E
1
Q
1
G
2
H
5
I
1
L
5
K
0
M
1
F
2
P
0
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 6 C: 0 E: 1 Q: 1 G: 1 H: 2 I: 5 L: 1 K: 5 M: 0 F: 1 P: 2 S: 0 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
31
C161H252N42O49
3560.02
5.27
-2
13.44
-0.968
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>=25 µM
Cytotoxic
50% Cytotoxicity | >=25 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo. | Antiviral Res | 2019