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Peptide record

TPDB21199

Antibacterial Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB21199
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
IDWKKXLNAXKQIL
Physicochemical Analysis
C69H116N18O17
RCEGHMFPSTYV
K
1469.79
10.32
3
1
6
+2
1.44
-0.336
118.57
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
374.20
2
Residue Composition
number
1
A
0
R
1
N
1
D
0
C
0
E
1
Q
0
G
0
H
2
I
2
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 2 L: 2 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C69H116N18O17
1469.79
10.32
+2
1.44
-0.336
Evidence Records 2 records
Evidence 1 Activity

Activity

37.8% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
37.8% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity and stability of stapled helices of polybia-MP1. | Arch Pharm Res | 2017
Evidence 2 Activity

Activity

16.3% Hemolysis
Toxicity
12.5 µM
Hemolytic Cytotoxic
16.3% Hemolysis | 12.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP