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Peptide record

TPDB21194

Antibacterial Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB21194
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
IDWKKLLXAAKXIL
Physicochemical Analysis
C69H118N16O15
RNCEQGHMFPSTYV
LK
1411.79
10.32
3
1
8
+2
-0.29
0.564
153.57
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
389.58
0
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
2
I
3
L
3
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 3 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14
C69H118N16O15
1411.79
10.32
+2
-0.29
0.564
Evidence Records 2 records
Evidence 1 Activity

Activity

25% Hemolysis
Toxicity
80 µM
Hemolytic Cytotoxic
25% Hemolysis | 80 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity. | J Pept Sci | 2017
Evidence 2 Activity

Activity

33% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
33% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Intramolecular cyclization of the antimicrobial peptide Polybia-MPI with triazole stapling: influence on stability and bioactivity. | J Pept Sci | 2017